Radiation Oncology

Radiation Biology Research Laboratory (page 5)

VI. Resources

Department of Radiation Oncology


The Department of Radiation Oncology has a state-of-the-art research facility. The 1800 square feet laboratory space laboratory has designated working space for tissue culture, radioisotope usage and a complete RNA bench area and Fluorescent microscope equipped with Image analysis system. Laboratory contains chemical/fume hood, equipment for DNA, mRNA and protein analysis including Electrophoretic units, power supply units, a Westernblot transfer units, two gel drying system, NucTrap Push Columns, dual intensity UV transilluminator, PhotoMan direct copy system, Thermocycler, Hybridization oven and an automated microplate reader MRX-5000. The bench tops are equipped with vacuum, gas and air outlets. The laboratory is also equipped with common equipment including pH meter, water baths, Millipore water purification system, mettler balances, Refrigerators and Freezers (-20oC & -86oC). In addition, the laboratory has specially designed units for hypoxia and hyperthermia studies with controlled gas flow, temperature and oxygen levels, including a state of the art large capacity workstation for experiments under hypoxia (Modular Atmosphere Controlled System VA-500, equipped with bleeding chamber). In house maintenance services including computer resources, instrumentation, plumbing, and electricity are available in the same building for service as needed. Department of Radiation Oncology has the following shared facilities: a walk-in cold room, a dark room and film developer, autoclave/washing facilities, Scintillation counter, and a Phosphorimager (Fluor-STM MultiImager). Through membership in the San Antonio Cancer Institute (a collaboration between the UTHSCSA and CTRC), we have privileged access to several Core facilities providing services such as: mass spectroscopy equipped with state of the art mass spectrometry and proteomics instrumentation (directed by Dr. Weintraub, a collaborator on this project), biostatistics consultation), flow cytometry, peptide syntheses/sequencing, oligonucleotide synthesis, DNA sequencing, scale up tissue culture, transgenic mice development, cytogenetics, pathology/histology, animal care/veterinarian service, the UTHSCSA provides informatics, a machine shop, and engineering services.


The Radiation Oncology Department housing a GammaCell-40 137 Cesium irradiator for ionizing radiation exposure. It is available to all Investigators for a nominal charge.


The University of Texas Health Science Center at San Antonio has an accredited animal facility for housing laboratory animals. There are four veterinarians including a veterinary pathologist, and other husbandry support staff. All research concerning animals meet the approval of the Institutional Animal Care and Use Committee.


Institutional CORE facility


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